Changzhou Smart-Lifesciences Biotechnology Co.,Ltd.

rProtein L Beads is an affinity chromatography medium designed for purification of classes, subclasses and fragments of immunoglobulins from biological fluids and from cell culture media. The recombinant protein L ligand is immobilized to 4% agarose beads. 

Protein L is first isolated from the surface of bacterial species Peptostreptoccus magnus and now recombinant Protein L is obtained by gene recombination technology. Unlike Protein A and Protein G, which bind primarily through Fc regions of immunoglobulins, Protein L binds the variable region of antibodies kappa light chain and binds a wider range of Ig classes and subclasses. Protein L is therefore particular suitable for capture of a wide range of different-sized antibody fragments such as Fab fragments, single-chain variable fragments (Scfv) and domain antibodies (dAbs).